EnzIm2Flow project
The overall aim of the project is to design predictable immobilized robust enzymes by improving the stability, cofactor retention and controlling the orientation of the enzyme on the carrier surface and to use this in a two-phase continuous-flow industrially relevant process to obtain a higher STY under safer and more sustainable conditions than competitive batch processes.
Our project is supported by a user committee which involves different SMEs and a large company that cover the biocatalysis knowledge and value chain from enzyme development to production of speciality chemicals.
Producers of immobilized enzymes and carrier materials for biocatalytic processes:
ChiralVision is a well established producer of enzyme immobilization carriers and immobilized enzymes.
The biotech and chemical industry that use enzymes to create more sustainable industrial processes:
Innosyn produces HSA for cosmetics applications using the enzyme Ohy in a batch process, which will serve as a benchmark for the flow process that will be developed.
Evonik is one of the world’s leading speciality chemical companies. The company actively seeks to improve the sustainability of their processes.
GreenOil specializes in regeneration and valorisation of waste cooking oils for biofuels, cosmetics and the chemical industry.
Academic expertise on flow biocatalysis and biomanufacturing:
Silesian University of Technology in the person of Dr. Szymańska contributes expertise on siliceous monolithic carrier materials for biocatalytic flow reactions.
University of Palermo in the person of Dr. Lima contibutes expertise on process development.
